Consequently the applied voltage can be switched on for longer periods to generate more reliable measurement data. In the Zetasizer Nano ZSP, use of Malvern's patented Diffusion Barrier Technique protects the sample by isolating it from the electrode, as recommended in the ASTM standard. It has been shown that much of the aggregation takes place at the electrodes. These materials are often labile, especially when subjected to an electric field, and standard electrophoretic techniques can lead to measurement of the resulting aggregates rather than the native material. Published during 2012, standard guide ASTM E2865 deals with the measurement of mobility and zeta potential in systems containing biological material such as proteins, DNA, liposomes and other similar organic materials that possess particle sizes in the nanometer scale, below 100 nm. Malvern, UK | Posted on November 16th, 2012 High sensitivity Zetasizer Nano ZSP helps users meet new zeta potential measurement standard for biologics The instrument delivers unique performance specifications for both size and zeta potential measurement, employing an approach to zeta potential measurement that accords with the latest industry guidance. One of the most significant applications for Malvern Instruments' new Zetasizer Nano ZSP dynamic light scattering system is the highly sensitive measurement of the zeta potential, or electrophoretic mobility, of proteins. The folded capillary cell used in the Diffusion Barrier Technique for electrophoretic mobility measurement implemented in the Zetasizer Nano ZSP

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Malvern zetasizer nano zsp